CRO Services

CRO Services

Our Specialty is in vitro and in vivo safety pharmacology

  • Contracted by the FDA to provide ion channel screening services in support of the CiPA intiative
  • Recognized experts and thought leaders
  • Working with our clients do design studies
  • Putting results in context

…We don’t just provide data, we provide solutions

With decades of ion channel and in vivo experience, CytoBioScience is uniquely positioned to be your one stop shop for safety pharmacology. From the CiPA ion channel panel to stem cells to in vivo studies, all aspects of the safety characterization of your compounds can be carried out. We also offer GLP capabilities and dose formulation analysis.

  • With the use of our CytoPatch4 - the “hands-free” manual patch clamp platform, we also offer higher throughput ion channel screening services
  • With our portfolio of capabilities, we can support screening of compounds from discovery through IND enabling studies
  • We are proud to have been contracted by the FDA to provide ion channel screening services in support of the CiPA intiative

Safety Assays

Assay Details
Cardiac action potentials
  • native adult human
  • iPSC-CM
Cardiac ion channels
  • Native adult human
  • rabbit
  • guinea pig
  • canine
  • rat
  • iPSC-CM
Langendorff prep
  • ECG
  • Cardiac Function
in vivo prep
  • Telemetry (invasive and non-invasive, ECG, systemic/ventricular pressures)
  • Cardiac output and function
  • Imaging (echo, CT, MRI, x-ray)
  • Anesthetized preps
  • Device assessment
  • Disease models
  • Multiple species (mice, rat, GP, canine, sheep)
Dose formulation analysis
  • GLP hERG
  • in vivo